You have to put a condensing unit somewhere with high velocity systems as well. Achieving high velocity requires a lot more energy, so you’ll be paying for it every month. Ductless mini splits are inherently zoned, where as high velocity systems can be zoned, but typically one air handler will serve your whole house, so you’ll be pushing high velocity air to zones that you’re not using, and unless you customize it to have zone dampers and modulate the air flow accordingly, you’ll be paying every month to condition spaces that you’re not even in. With ductless mini splits, you can just turn that cassette or wall mounted unit off. Ductless minisplits also have a VRF application where a single condenser can serve multiple indoor units. I’ve never spec’d a VRF system, but it might be worth looking into.
I prefer ductless mini splits over conventional and high velocity systems.